{{Genotype
|rsid=1061147
|allele1=A
|allele2=A
|magnitude=2
|repute=Bad
|summary=2.76x increased risk for Age Related Macular Degeneration.
}}
When the retina cells in the eye get damaged with age, it is known as Age Related Macular Degeneration. This SNP has about three times the normal risk. This SNP wrecks the brakes on the complementary immune system, so it can become out of control, resulting in inflamation that damages the cells in the eye. 
The SENS Research Foundation is working on a promising cure for Age Related Macular Degeneration: http://www.sens.org/outreach/conferences/lysosens-synthetic-biology-approach-treat-age-related-macular-degeneration