{{Genotype
|rsid=11978267
|allele1=G
|allele2=G
|magnitude=2
|repute=Bad
|summary=possible increased risk for infant acute myeloid leukemia (AML)
}}

Although based on a fairly small study (~170 pediatric patients), homozygosity for this relatively rare IKZF1 gene allele has been reported to increase risk (perhaps 3+ fold) of infant acute myeloid leukemia (AML).