{{Genotype
|allele1=G
|allele2=G
|rsid=1861046
|gene=C1QTNF7
|Chromosome=4
|magnitude=1
}}

[[Conduct disorder]] (CD) is one of the most prevalent childhood psychiatric conditions, and is associated with a number of serious concomitant and future problems. CD symptomatology is known to have a considerable genetic component, with heritability estimates in the range of 50%.

Four SNPs reached genome-wide significance with CD symptom count, based on P < 5x10^-8 Two of these SNPs ([[rs16891867]] and [[rs1861046]]) were in the gene C1QTNF7 (C1q and tumor necrosis factor-related protein 7). These SNPs were in high LD (r^2=0.97).  The other top two SNPs meeting genome-wide significance were intergenic and located on chromosomes 11 and 13.  Alleles A/G were found to be associated with CD symptom count or CD case status.


[http://www.downstate.edu/hbnl/documents/2010-Dick-Genome-wideassociationstudyofconductdisordersymptomatology.pdf]