{{Genotype
|rsid=2032583
|allele1=C
|allele2=C
|magnitude=1.9
|repute=Good
|summary=7x more likely to respond to certain antidepressants.
}}
This version of a blood brain barrier protein helps many common antidepressants to enter the brain, including: amitriptyline (Elavil), citalopram (Celexa), paroxetine (Paxil), and venlafaxine (Effexor). That makes those antidepressants 7 times more effective.