{{Genotype
|rsid=2243093
|allele1=C
|allele2=C
|magnitude=3.4
|repute=Bad
}}
A case-control study of Chinese Han patients reported that the [[rs2243093]] (C;C) genotype has an increase risk for coronary heart disease. A meta-analysis was performed and found that there is a strong association with risk of ischemic stroke, however, the authors suggest that this polymorphism may actually be linked with another (unknown) locus that is the culprit responsible for the increase in ischemic stroke risk.