{{Genotype
|rsid=2300478
|allele1=G
|allele2=G
|magnitude=2
|repute=Bad
|summary=>1.7x risk for developing restless legs syndrome
}}

Variants in MEIS1 [[rs2300478]], BTBD9 [[rs9357271]], and MAP2K5/SKOR1 [[rs1026732]] confer a significant risk of RLS in a US population. {{PMID|21925394}}

{{PMID|21925394}}  Association studies of variants in MEIS1, BTBD9, and MAP2K5/SKOR1 with restless legs syndrome in a US population.