{{Genotype
|rsid=2395185
|allele1=G
|allele2=G
|magnitude=2
|repute=Good
|summary=1.33x increased risk of Ulcerative Colitis, but much lower Type 1 Diabetes risk.
}}
This raises the risk of Ulcerative Colitis (according to 23andMe), but also greatly lowers the risk of Type 1 Diabetes.{{PMID|19837788}} It may also affect other autoimmune diseases.