{{Genotype
|rsid=2395185
|allele1=G
|allele2=T
|magnitude=2
|repute=Bad
|summary=2.72x higher risk of Type 1 Diabetes, but 0.88x lower risk of Ulcerative Colitis.
}}
This lowers the risk of Ulcerative Colitis (according to 23andMe), and increases the risk of Type 1 Diabetes.[PMID 19837788] It may also affect other autoimmune diseases.