{{Rsnum
|rsid=10008492
|Chromosome=4
|position=38764099
|Orientation=plus
|GMAF=0.2576
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 38.1 | 48.7 | 13.3
| HCB | 0.0 | 0.0 | 100.0
| JPT | 0.0 | 0.0 | 100.0
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 15.8 | 84.2
| CHB | 0.0 | 0.0 | 100.0
| CHD | 0.0 | 0.9 | 99.1
| GIH | 0.0 | 10.9 | 89.1
| LWK | 0.0 | 0.0 | 0.0
| MEX | 3.5 | 22.8 | 73.7
| MKK | 0.0 | 1.3 | 98.7
| TSI | 25.7 | 44.6 | 29.7
| HapMapRevision=28
}}[[rs10008492]] is a SNP located in a cluster of toll-like receptor genes.

In a pooled analysis including three population-based case-control studies of [[Non-Hodgkin's lymphoma]] (1,946 cases, 1,808 controls), two SNPs in moderate linkage disequilibrium were significantly associated with NHL: [[rs10008492]] (odds ratio for (C;T) genotype 1.12, CI: 0.97-1.30; OR(T;T) 1.40, CI: 1.15-1.71; p(trend)=0.001) and [[rs4833103]] (OR(A;C) 0.75, CI: 0.64-0.88; OR(A;A) 0.74, CI: 0.62-0.90; p(trend)=0.002; p(dominant)=0.0002).{{PMID|19029192|OA=1
}}

{{PMID|19503599|OA=1
}} The impact of divergence time on the nature of population structure: an example from Iceland.

{{PMID|20200442|OA=1
}} Sequence variants in the TLR4 and TLR6-1-10 genes and prostate cancer risk. Results based on pooled analysis from three independent studies.

{{PMID|21872627}} Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk.

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}