{{Rsnum
|rsid=1001179
|Gene=CAT
|Chromosome=11
|position=34438684
|Orientation=minus
|GMAF=0.123
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=CAT
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 3.6 | 40.5 | 55.9
| HCB | 0.0 | 5.8 | 94.2
| JPT | 0.0 | 5.3 | 94.7
| YRI | 0.0 | 2.0 | 98.0
| ASW | 0.0 | 7.1 | 92.9
| CHB | 0.0 | 5.8 | 94.2
| CHD | 0.9 | 7.3 | 91.7
| GIH | 2.0 | 34.7 | 63.4
| LWK | 0.9 | 4.6 | 94.5
| MEX | 6.9 | 25.9 | 67.2
| MKK | 0.0 | 11.5 | 88.5
| TSI | 4.9 | 32.4 | 62.7
| HapMapRevision=28
}}
A study of non-Hispanic Caucasians with various types of brain tumors concluded that there was an decreased risk of acoustic neuroma (odds ratio 0.6, CI: 0.3-1.0) associated with the [[rs1001179]](A) allele, as oriented in dbSNP orientation (and not as published).{{PMID|18682580|OA=1
}}

{{PMID Auto
|PMID=19863340
|Title=Influence of the polymorphism in candidate genes on late cardiac damage in patients treated due to acute leukemia in childhood
}}

{{PMID Auto
|PMID=20110814
|Title=Air pollution and homocysteine: more evidence that oxidative stress-related genes modify effects of particulate air pollution
|OA=1
}}

{{PharmGKB
|RSID=rs1001179
|Name_s=CAT -262C > T; CAT:(-262)C>T
|Gene_s=CAT
|Feature=
|Evidence=PubMed ID:19863340
|Annotation=Risk or phenotype-associated allele: Phenotype: This SNP was not found to be associated with anthracyline related cardiotoxicity. Study size: 76 Study population/ethnicity: Survivors of childhood leukemia (Precursor Cell Lymphoblastic Leukemia-Lymphoma), Slovenia
|Drugs=
|Drug Classes=ANTHRACYCLINES AND RELATED SUBSTANCES
|Diseases=Cardiomyopathies; Drug Toxicity; Precursor Cell Lymphoblastic Leukemia-Lymphoma
|Curation Level=Curated
|PharmGKB Accession ID=PA165291528
}}

{{PMID Auto
|PMID=21795425
|Title=Genetic Variation in Myeloperoxidase Modifies the Association of Serum {alpha}-Tocopherol with Aggressive Prostate Cancer among Current Smokers
|OA=1
}}

{{PMID Auto
|PMID=21338322
|Title=Parameters of oxidative stress, DNA damage and DNA repair in type 1 and type 2 diabetes mellitus
}}

{{PMID Auto
|PMID=22712453
|Title=Effects of rs769217 and rs1001179 polymorphisms of catalase gene on blood catalase, carbohydrate and lipid biomarkers in diabetes mellitus
}}

{{PMID Auto
|PMID=16385446
|Title=A testing framework for identifying susceptibility genes in the presence of epistasis.
|OA=1
}}

{{PMID Auto
|PMID=16453382
|Title=No evidence for a major effect of two common polymorphisms of the catalase gene in type 1 diabetes susceptibility.
}}

{{PMID Auto
|PMID=16820586
|Title=Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery.
|OA=1
}}

{{PMID Auto
|PMID=18248894
|Title=Short arm of chromosome 11 and sporadic Alzheimer's disease: catalase and cathepsin D gene polymorphisms.
}}

{{PMID Auto
|PMID=18483329
|Title=Effect modification by catalase genotype suggests a role for oxidative stress in the association of hormone replacement therapy with postmenopausal breast cancer risk.
}}

{{PMID Auto
|PMID=18606005
|Title=Detection of catalase as a major protein target of the lipid peroxidation product 4-HNE and the lack of its genetic association as a risk factor in SLE.
|OA=1
}}

{{PMID Auto
|PMID=18988661
|Title=Glutathione-S-transferase (GST) P1, GSTM1, exercise, ozone and asthma incidence in school children.
|OA=1
}}

{{PMID Auto
|PMID=19505917
|Title=Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumors.
|OA=1
}}

{{PMID Auto
|PMID=20049130
|Title=Black carbon exposure, oxidative stress genes, and blood pressure in a repeated-measures study.
|OA=1
}}

{{PMID Auto
|PMID=20445800
|Title=Genetic Polymorphisms in Genes Related to Oxidative Stress (GSTP1, GSTM1, GSTT1, CAT, MnSOD, MPO, eNOS) and Survival of Rectal Cancer Patients after Radiotherapy.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1001179
|overall_frequency_n=15
|overall_frequency_d=116
|overall_frequency=0.12931
|n_genomes=8
|n_genomes_annotated=0
|n_haplomes=10
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23961996
|Title=A catalase promoter variant rs1001179 is associated with visual acuity but not with primary angle closure glaucoma in Saudi patients
|OA=1
}}

{{PMID Auto
|PMID=23363810
|Title=Prostate disease risk factors among a New Zealand cohort
}}

{{PMID Auto
|PMID=24215654
|Title=Analysis of Catalase SNP rs1001179 in Saudi patients with Primary Open Angle Glaucoma
}}

{{PMID Auto
|PMID=23053794
|Title=Polymorphisms in oxidative stress genes, physical activity, and breast cancer risk.
|OA=1
}}

{{PMID Auto
|PMID=23325794
|Title=Genetic polymorphisms in catalase and CYP1B1 determine DNA adduct formation by benzo(a)pyrene ex vivo.
}}

{{PMID Auto
|PMID=25248722
|Title=Genetic Polymorphism of CAT C-262 T and Susceptibility to Breast Cancer, a Case-Control Study and Meta-Analysis of the Literatures
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}