{{Rsnum
|rsid=10012946
|Gene=WFS1
|Chromosome=4
|position=6291623
|Orientation=plus
|GMAF=0.2677
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=WFS1
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 42.9 | 50.9 | 6.2
| HCB | 93.4 | 6.6 | 0.0
| JPT | 93.8 | 6.2 | 0.0
| YRI | 49.7 | 42.8 | 7.6
| ASW | 45.6 | 42.1 | 12.3
| CHB | 93.4 | 6.6 | 0.0
| CHD | 87.2 | 12.8 | 0.0
| GIH | 42.0 | 52.0 | 6.0
| LWK | 43.6 | 46.4 | 10.0
| MEX | 57.1 | 37.5 | 5.4
| MKK | 47.4 | 42.2 | 10.4
| TSI | 42.2 | 42.2 | 15.7
| HapMapRevision=28
}}

{{Report GE
|PubMed=17603484
|Source=journal
|AffyProbeset=SNP_A-2232157
|AffyOrientation=same
|AlleleA=C
|AlleleB=T
|onGW5=1
|rsid=10012946
|ancestral=T
|RiskPopulation=Caucasian (UK)
|RiskAllele=C
|CaseFreq=
|ControlFreq=
|OddsRatioHet=
|OddsRatioHom=
|OddsRatioAll=1.15
|Disease=Type II Diabetes
|DiseaseSymbol=T2D
|OA=1
}}

rs10012946 is in linkage disequilibrium with a polymorphism that increases susceptibility to Type II Diabetes 1.15 times for carriers of the C allele {{PMID|17603484|OA=1
}}

{{PMID|18060660|OA=1
}} Testing of diabetes-associated WFS1 polymorphisms in the Diabetes Prevention Program.

{{PMID|18426861|OA=1
}} Association analysis of type 2 diabetes Loci in type 1 diabetes.

{{PMID|18694974|OA=1
}} Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study.

{{PMID|19096518|OA=1
}} Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study.

{{PMID|19341491|OA=1
}} Genome-based prediction of common diseases: methodological considerations for future research.

{{PMID|20018041|OA=1
}} The effect of multiple genetic variants in predicting the risk of type 2 diabetes.

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | Affy500k}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}