{{Rsnum
|rsid=10088218
|Chromosome=8
|position=128531703
|Orientation=plus
|GMAF=0.08448
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}[[rs10088218]] is a SNP on chromosome 8q24, >700 kb distal to the [[CMYC]] gene in an area termed a 'gene desert'. 

A genome-wide association study ultimately including over 10,000 [[ovarian cancer]] patients found statistically strong (p = 8 × 10e-15) evidence for slightly reduced risk associated with the [[rs10088218]](A) allele, with an odds ratio of 0.76 (CI: 0.7 – 0.81) as calculated for the serous subtype (of ovarian cancer).{{PMID|20852632|OA=1
}}

{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.9 | 23.2 | 75.9
| HCB | 0.0 | 2.9 | 97.1
| JPT | 0.0 | 0.9 | 99.1
| YRI | 1.4 | 22.4 | 76.2
| ASW | 3.5 | 21.1 | 75.4
| CHB | 0.0 | 2.9 | 97.1
| CHD | 0.0 | 2.8 | 97.2
| GIH | 0.0 | 10.9 | 89.1
| LWK | 0.9 | 22.7 | 76.4
| MEX | 0.0 | 12.1 | 87.9
| MKK | 2.6 | 15.4 | 82.1
| TSI | 2.0 | 15.7 | 82.4
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=20852632
|Trait=None
|Title=A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24
|RiskAllele=G
|Pval=3E-9
|OR=1.19
|ORtxt=[1.12-1.25]
|OA=1
}}

{{PMID Auto
|PMID=22235027
|Title=Evaluation of microRNA expression profiles and their associations with risk alleles in lymphoblastoid cell lines of familial ovarian cancer.
|OA=1
}}

{{PMID Auto
|PMID=22253144
|Title=Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers.
|OA=1
}}

{{PMID Auto GWAS
  |PMID=23535730
  |Trait=Ovarian cancer
  |Title=GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.
  |RiskAllele=
  |Pval=1E-17
  |OR=1.29
  |ORtxt=[1.21-1.36]
  |OA=1
}}

{{PMID Auto
|PMID=23133607
|Title=Associations between gene expression variations and ovarian cancer risk alleles identified from genome wide association studies.
|OA=1
}}

{{PMID Auto
|PMID=25173882
|Title=Replication Study for the Association of Seven Genome- Gwas-Identified Loci With Susceptibility to Ovarian Cancer in the Polish Population
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}