{{Rsnum
|rsid=1009668
|Gene=TMEM63A
|Chromosome=1
|position=225852703
|Orientation=minus
|ReferenceAllele=G
|MissenseAllele=A
|GMAF=0.1006
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=TMEM63A
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.9 | 15.0 | 84.1
| HCB | 0.7 | 27.7 | 71.5
| JPT | 0.9 | 10.6 | 88.5
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 7.0 | 93.0
| CHB | 0.7 | 27.7 | 71.5
| CHD | 3.7 | 12.8 | 83.5
| GIH | 0.0 | 5.9 | 94.1
| LWK | 0.0 | 0.0 | 0.0
| MEX | 1.7 | 34.5 | 63.8
| MKK | 0.0 | 0.0 | 0.0
| TSI | 2.0 | 20.6 | 77.5
| HapMapRevision=28
}}{{PMID|19111454|OA=1
}} [[rs1009668]] was significantly (p = 0.04) associated with bronchodilator responsiveness among patients with severe [[chronic obstructive pulmonary disease]]

{{PMID Auto
|PMID=17686149
|Title=Xenobiotic metabolizing enzyme gene polymorphisms predict response to lung volume reduction surgery.
|OA=1
}}

{{GET Evidence
|gene=TMEM63A
|aa_change=Val622Met
|aa_change_short=V622M
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1009668
|overall_frequency_n=781
|overall_frequency_d=10758
|overall_frequency=0.0725971
|n_genomes=8
|n_genomes_annotated=0
|n_haplomes=8
|n_articles=0
|n_articles_annotated=0
|nblosum100=0
|autoscore=0
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}