{{Rsnum
|rsid=10116277
|Gene=CDKN2B-AS1
|Chromosome=9
|position=22081398
|Orientation=plus
|GMAF=0.3466
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=CDKN2B-AS1
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 30.1 | 48.7 | 21.2
| HCB | 10.4 | 49.3 | 40.3
| JPT | 9.7 | 38.9 | 51.3
| YRI | 0.0 | 3.4 | 96.6
| ASW | 0.0 | 21.1 | 78.9
| CHB | 10.4 | 49.3 | 40.3
| CHD | 10.2 | 39.8 | 50.0
| GIH | 19.8 | 54.5 | 25.7
| LWK | 0.0 | 7.3 | 92.7
| MEX | 22.4 | 51.7 | 25.9
| MKK | 0.6 | 5.8 | 93.6
| TSI | 14.7 | 55.9 | 29.4
| HapMapRevision=28
}}discussed in this [http://suicyte.wordpress.com/2007/05/26/soul-searching-i/ blog post]A region of chromosome 9p21 has revealed numerous SNPs correlated with risk of [[myocardial infarction]] in a study of 2,000+ patients. This SNP, [[rs10116277]], is highly correlated (r<sup>2</sup>=0.9) with [[rs2383207]], as well as [[rs1333040]] (r<sup>2</sup>=0.67). Ultimately, though, the SNP in this study (and region) with the highest disease correlation is [[rs10757278]].

According to a DeCode report, the G allele of his SNP is associated with lower risk of [[abdominal aortic aneurysm]] (AAA). {{PMID|18176561}}

{{ neighbor
| rsid = 1333040
| distance = 2007
}}

{{ neighbor
| rsid = 6475606
| distance = 453
}}

{{omim
|id=611139
|rsnum=10116277
}}

{{PMID Auto
|PMID=21375403
|Title=The Relationship Between Polymorphisms on Chromosome 9p21 and Age of Onset of Coronary Heart Disease in Black and White Women
|OA=1
}}

{{PMID Auto
|PMID=18362232
|Title=Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease.
|OA=1
}}

{{PMID Auto
|PMID=18620593
|Title=Investigation of 89 candidate gene variants for effects on all-cause mortality following acute coronary syndrome.
|OA=1
}}

{{PMID Auto
|PMID=18704761
|Title=Molecular genetics of myocardial infarction.
|OA=1
}}

{{PMID Auto
|PMID=18987759
|Title=Genetic testing for atherosclerosis risk: inevitability or pipe dream?
|OA=1
}}

{{PMID Auto
|PMID=19463184
|Title=Worldwide patterns of haplotype diversity at 9p21.3, a locus associated with type 2 diabetes and coronary heart disease.
|OA=1
}}

{{PMID Auto
|PMID=19819472
|Title=Common genetic variants on chromosome 9p21 predict perioperative myocardial injury after coronary artery bypass graft surgery.
|OA=1
}}

{{PMID Auto
|PMID=19888323
|Title=Relationship between CAD risk genotype in the chromosome 9p21 locus and gene expression. Identification of eight new ANRIL splice variants.
|OA=1
}}

{{PMID Auto
|PMID=20386740
|Title=Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression.
|OA=1
}}

{{PMID Auto
|PMID=20718794
|Title=Association of polymorphisms in 9p21 region with CAD in North Indian population: replication of SNPs identified through GWAS.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | Illumina Human 1M}}