{{Rsnum
|rsid=1013579
|Gene=C8B
|Chromosome=1
|position=56956811
|Orientation=plus
|ReferenceAllele=G
|MissenseAllele=A
|GMAF=0.01882
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=C8B
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 92.9 | 7.1 | 0.0
| HCB | 100.0 | 0.0 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 100.0 | 0.0 | 0.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 100.0 | 0.0 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 99.1 | 0.9 | 0.0
| MEX | 89.7 | 10.3 | 0.0
| MKK | 96.2 | 3.8 | 0.0
| TSI | 90.2 | 8.8 | 1.0
| HapMapRevision=28
}}

{{Venter SNP
|rsid=1013579
|allele=T
|frequency=0.95
|uid=1103675100407
|type=homozygous_SNP
|hugo=C8B
|ensembl gene=ENSG00000021852
|ensembl transcript=ENST00000371237
|sift=TOLERATED
|disease=Defects in C8B are a cause of complement C8 deficiency type II (MIM:120960). Patients with deficiency of C8 suffer from recurrent bacterial infections, predominantly from Neisseria meningitidis.
}}

{{GET Evidence
|gene=C8B
|aa_change=Gly117Arg
|aa_change_short=G117R
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1013579
|overall_frequency_n=10494
|overall_frequency_d=10758
|overall_frequency=0.97546
|n_genomes=56
|n_genomes_annotated=0
|n_haplomes=109
|n_articles=0
|n_articles_annotated=0
|nblosum100=6
|autoscore=0
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}