{{Rsnum
|rsid=1016343
|Chromosome=8
|position=127081052
|Orientation=plus
|GMAF=0.2149
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene=PRNCR1
|Gene_s=PRNCR1
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 54.0 | 39.8 | 6.2
| HCB | 43.8 | 42.3 | 13.9
| JPT | 50.4 | 43.4 | 6.2
| YRI | 56.5 | 34.0 | 9.5
| ASW | 70.2 | 28.1 | 1.8
| CHB | 43.8 | 42.3 | 13.9
| CHD | 46.3 | 44.4 | 9.3
| GIH | 66.3 | 30.7 | 3.0
| LWK | 67.3 | 28.2 | 4.5
| MEX | 77.6 | 22.4 | 0.0
| MKK | 60.9 | 31.4 | 7.7
| TSI | 59.8 | 37.3 | 2.9
| HapMapRevision=28
}}[http://cancergenetics.wordpress.com/2008/02/15/prostate-cancer-oldnew-snps-and-decodeprca/ cancer-genetics] these snps influence genetic risk for [[prostate cancer]]
*the [[haplotype]] [[rs6983267]] [[rs1016343]] [[rs4242384]] 
*[[rs7501939]] 
*[[rs1859962]]
*[[rs2660753]]
*[[rs9364554]]
*[[rs6465657]]
*[[rs10993994]]
*[[rs7931342]]
*[[rs2735839]]
*[[rs5945619]]
*[[rs10993994]]

{{PMID Auto GWAS
|PMID=18264097
|Trait=Prostate cancer
|Title=Multiple newly identified loci associated with prostate cancer susceptibility
|RiskAllele=T
|Pval=9.9999999999999995E-8
|OR=1.37
|ORtxt=[NR]
}}

{{PMID Auto
|PMID=19866473
|Title=Association of 17 prostate cancer susceptibility loci with prostate cancer risk in Chinese men
|OA=1
}}

{{PMID Auto GWAS
|PMID=21743057
|Trait=None
|Title=Genome-wide association study identifies new prostate cancer susceptibility loci.
|RiskAllele=T
|Pval=4E-10
|OR=1.3100
|ORtxt=[1.20-1.42]
|OA=1
}}

{{PMID Auto
|PMID=22733159
|Title=Analysis of prostate cancer association with four single-nucleotide polymorphisms from genome-wide studies and serum phyto-estrogen concentrations
}}

{{PMID|18483343}} Multiple independent genetic variants in the 8q24 region are associated with prostate cancer risk.

{{PMID|18535017|OA=1
}} Pooled analysis of genetic variation at chromosome 8q24 and colorectal neoplasia risk.

{{PMID|19549807|OA=1
}} Prostate cancer risk associated loci in African Americans.

{{PMID|20039378|OA=1
}} Estimation of genotype relative risks from pedigree data by retrospective likelihoods.

{{PMID|20690139}} Meta-analysis of genome-wide and replication association studies on prostate cancer.

{{PMID|21390317|OA=1
}} Characterizing associations and SNP-environment interactions for GWAS-identified prostate cancer risk markers--results from BPC3.

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1016343
|overall_frequency_n=34
|overall_frequency_d=128
|overall_frequency=0.265625
|n_genomes=23
|n_genomes_annotated=0
|n_haplomes=27
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=24779299
|Title=Study of genetic variants of 8q21 and 8q24 associated with prostate cancer in Jing-Jin residents in northern China
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}