{{Rsnum
|rsid=10409962
|Gene=SIGLEC8
|Chromosome=19
|position=51457686
|Orientation=plus
|GMAF=0.2075
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=SIGLEC8
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 93.8 | 6.2 | 0.0
| HCB | 84.2 | 15.0 | 0.8
| JPT | 83.2 | 15.9 | 0.9
| YRI | 17.0 | 44.9 | 38.1
| ASW | 28.1 | 54.4 | 17.5
| CHB | 84.2 | 15.0 | 0.8
| CHD | 79.8 | 19.3 | 0.9
| GIH | 89.1 | 10.9 | 0.0
| LWK | 18.3 | 42.2 | 39.4
| MEX | 77.6 | 20.7 | 1.7
| MKK | 21.8 | 53.2 | 25.0
| TSI | 83.3 | 15.7 | 1.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=20087405
|Title=Polymorphisms in the sialic acid-binding immunoglobulin-like lectin-8 (Siglec-8) gene are associated with susceptibility to asthma
|OA=1
}}

{{GET Evidence
|gene=SIGLEC8
|aa_change=Ser170Pro
|aa_change_short=S170P
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs10409962
|overall_frequency_n=2312
|overall_frequency_d=10758
|overall_frequency=0.21491
|n_genomes=20
|n_genomes_annotated=0
|n_haplomes=31
|n_articles=0
|n_articles_annotated=0
|nblosum100=3
|autoscore=0
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}