{{Rsnum
|rsid=1041296
|Chromosome=10
|position=132003031
|Orientation=minus
|GMAF=0.1685
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}
{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 0.0 | 19.8 | 80.2
| HCB | 1.5 | 21.5 | 77.0
| JPT | 3.5 | 18.6 | 77.9
| YRI | 17.0 | 42.9 | 40.1
| ASW | 8.9 | 55.4 | 35.7
| CHB | 1.5 | 21.5 | 77.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 13.9 | 54.6 | 31.5
| MEX | 0.0 | 13.8 | 86.2
| MKK | 9.7 | 46.5 | 43.9
| TSI | 1.0 | 12.9 | 86.1
| HapMapRevision=28
}}
[http://genetics.plosjournals.org/perlserv/?request=get-document&doi=10.1371%2Fjournal.pgen.0030120.eor linked] to Cardiovascular Events

Several CVD risk variants were identified: In women, the combination of F5 [[rs7542281]] Ã— THBD [[rs1042580]], together with three single F5 SNPs, was associated with CVD events. Among men, PROC [[rs1041296]], when combined with either ICAM1 [[rs5030341]] or F5 [[rs2269648]], was associated with total mortality. As a single variant, PROC [[rs1401296]], together with the F5 Leiden mutation, was associated with ischemic [[stroke]] events. {{PMID|17677000|OA=1
}}

'''NOTE:''' SNPedia has raised a question with the authors of this paper ({{PMID|17677000|OA=1
}}), in that it appears that their mention of "rs1041296" is a typographical error, when they intended to refer to SNP [[rs1401296]]. Once a response is received from the authors, we will update the associated entries, and until then, ''Caveat Emptor''.

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}