{{Rsnum
|rsid=1042114
|Gene=OPRD1
|Chromosome=1
|position=28812463
|Orientation=plus
|ReferenceAllele=G
|MissenseAllele=T
|GMAF=0.06841
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=OPRD1
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 0.9 | 22.1 | 77.0
| HCB | 0.0 | 0.0 | 100.0
| JPT | 0.0 | 0.0 | 100.0
| YRI | 0.0 | 4.8 | 95.2
| ASW | 0.0 | 8.8 | 91.2
| CHB | 0.0 | 0.0 | 100.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 10.9 | 89.1
| LWK | 0.0 | 4.5 | 95.5
| MEX | 0.0 | 8.6 | 91.4
| MKK | 0.0 | 3.2 | 96.8
| TSI | 2.0 | 22.5 | 75.5
| HapMapRevision=28
}}rs1042114 increases susceptibility to Substance dependence, Opioid 3.56 times for carriers of the G allele {{PMID|17622222|OA=1
}}

{{omim
|desc=OPIOID RECEPTOR, DELTA-1; OPRD1
|id=165195
|rsnum=1042114
}}

{{omim
|id=103780
|rsnum=1042114
}}

{{PMID Auto
|PMID=18518925
|Title=Genetic susceptibility to heroin addiction: a candidate gene association study.
|OA=1
}}

{{PMID Auto
|PMID=21423693
|Title=Effect sizes in experimental pain produced by gender, genetic variants and sensitization procedures.
|OA=1
}}

{{GET Evidence
|gene=OPRD1
|aa_change=Cys27Phe
|aa_change_short=C27F
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1042114
|overall_frequency_n=8471
|overall_frequency_d=9230
|overall_frequency=0.917768
|n_genomes=13
|n_genomes_annotated=0
|n_haplomes=21
|n_articles=0
|n_articles_annotated=0
|nblosum100=4
|autoscore=0
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}