{{Rsnum
|rsid=1042173
|Gene=SLC6A4
|Chromosome=17
|position=30197993
|Orientation=minus
|GMAF=0.494
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=SLC6A4
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 13.3 | 58.4 | 28.3
| HCB | 73.0 | 21.9 | 5.1
| JPT | 63.7 | 32.7 | 3.5
| YRI | 2.7 | 29.9 | 67.3
| ASW | 1.8 | 43.9 | 54.4
| CHB | 73.0 | 21.9 | 5.1
| CHD | 68.8 | 29.4 | 1.8
| GIH | 32.7 | 43.6 | 23.8
| LWK | 6.4 | 28.2 | 65.5
| MEX | 36.2 | 51.7 | 12.1
| MKK | 1.3 | 17.9 | 80.8
| TSI | 28.4 | 51.0 | 20.6
| HapMapRevision=28
}}[[rs1042173]] is a SNP in the solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 [[SLC6A4]] gene.

A study of 275 patients seeking treatment for [[alcoholism]] concluded that Caucasians of with the [[rs1042173]](T;T) genotype consumed an average of 11.17 drinks per drinking day, compared with an average of 8.58 for carriers of a [[rs1042173]](G) allele (p = 0.0034). While this held true for both men and women, this association was not seen in Hispanics. {{PMID|19032574|OA=1
}}

{{PMID Auto
|PMID=21247998
|Title=Pharmacogenetic Approach at the Serotonin Transporter Gene as a Method of Reducing the Severity of Alcohol Drinking
|OA=1
}}

{{PMID Auto
|PMID=21585624
|Title=Association of haplotype combination of serotonin transporter gene polymorphisms with monthly headache days in MOH patients
}}

{{PMID Auto
|PMID=22355291
|Title=Preliminary Evidence for cue-induced Alcohol Craving Modulated by Serotonin Transporter Gene Polymorphism rs1042173.
|OA=1
}}

{{PMID Auto
|PMID=15361494
|Title=Association between a functional polymorphism in the serotonin transporter gene and diarrhoea predominant irritable bowel syndrome in women.
|OA=1
}}

{{PMID Auto
|PMID=17999363
|Title=Multifactor dimensionality reduction-phenomics: a novel method to capture genetic heterogeneity with use of phenotypic variables.
|OA=1
}}

{{PMID Auto
|PMID=18486105
|Title=New evidence for the association of the serotonin transporter gene (SLC6A4) haplotypes, threatening life events, and depressive phenotype.
}}

{{PMID Auto
|PMID=19141529
|Title=Serotonin transporter polymorphisms in patients with portopulmonary hypertension.
|OA=1
}}

{{PMID Auto
|PMID=19199283
|Title=Variants of the serotonin transporter gene and NEO-PI-R Neuroticism: No association in the BLSA and SardiNIA samples.
|OA=1
}}

{{PMID Auto
|PMID=20395645
|Title=Association study of serotonin transporter gene (SLC6A4) in systemic sclerosis in European Caucasian populations.
}}

{{PMID Auto
|PMID=21290142
|Title=Parent of origin effect and allelic expression imbalance of the serotonin transporter in bipolar disorder and suicidal behaviour.
}}

{{PMID Auto
|PMID=23484320
|Title=[Relationship between genetic polymorphisms of 3 SNP loci in 5-HTT gene and paranoid schizophrenia]
}}

{{PMID Auto
|PMID=23558235
|Title=Independent effects of 5' and 3' functional variants in the serotonin transporter gene on suicidal behavior in the context of childhood trauma
}}

{{PMID Auto
|PMID=23757001
|Title=Association, interaction, and replication analysis of genes encoding serotonin transporter and 5-HT3 receptor subunits A and B in alcohol dependence
}}

{{PMID Auto
|PMID=23290502
|Title=Serotonin transporter and receptor genes significantly impact nicotine dependence through genetic interactions in both European American and African American smokers
|OA=1
}}

{{PMID Auto
|PMID=22727904
|Title=Sex determines which section of the SLC6A4 gene is linked to obsessive-compulsive symptoms in normal Chinese college students.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}