{{Rsnum
|rsid=1042858
|Gene=RRM1
|Chromosome=11
|position=4138236
|Orientation=plus
|GMAF=0.1575
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=RRM1
}}{{PharmGKB
|RSID=rs1042858
|Name_s=RRM1:2464G>A; rs1042858
|Gene_s=RRM1
|Feature=Exon/Syn
|Evidence=PubMed ID:17602053
|Annotation=A haplotype of RRM1 (2455 A>G and 2464 G>A) was associated with a lower frequency of neutropenia in advanced breast cancer patients treated with gemcitabine.
|Drugs=gemcitabine
|Drug Classes=
|Diseases=Breast Neoplasms
|Curation Level=Curated
|PharmGKB Accession ID=PA162355484
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1042858
|overall_frequency_n=9569
|overall_frequency_d=10758
|overall_frequency=0.889478
|n_genomes=27
|n_genomes_annotated=0
|n_haplomes=48
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}