{{Rsnum
|rsid=10446073
|Gene=C21orf91
|Chromosome=21
|position=17820455
|Orientation=plus
|GMAF=0.05326
|Gene_s=C21orf91
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 87.6 | 12.4 | 0.0
| HCB | 95.5 | 4.5 | 0.0
| JPT | 93.5 | 6.5 | 0.0
| YRI | 81.9 | 18.1 | 0.0
| ASW | 76.8 | 21.4 | 1.8
| CHB | 95.5 | 4.5 | 0.0
| CHD | 96.2 | 3.8 | 0.0
| GIH | 91.1 | 6.9 | 2.0
| LWK | 81.1 | 18.9 | 0.0
| MEX | 86.0 | 14.0 | 0.0
| MKK | 80.0 | 18.7 | 1.3
| TSI | 96.9 | 3.1 | 0.0
| HapMapRevision=28
}}{{PMID|22039568|OA=1
}} http://jid.oxfordjournals.org/content/204/11/1654.long 
This analysis revealed a strong association between the frequently affected phenotype and the C allele of SNP [[rs1062202]] (?2 = 8.0, P = .0047), predicted to lie in the 3? UTR of C21orf91 (Figure 2, Table 1). Another SNP, [[rs10446073]], which was approximately 1 kb upstream of the start site of transcription of C21orf91, also showed a moderate association (?2 = 3.57, P = .06) with the cold-sore phenotype.

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}