{{Rsnum
|rsid=1046089
|Gene=PRRC2A
|Chromosome=6
|position=31635190
|Orientation=plus
|GMAF=0.3944
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=PRRC2A
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 8.8 | 42.5 | 48.7
| HCB | 14.6 | 53.3 | 32.1
| JPT | 13.3 | 42.5 | 44.2
| YRI | 39.9 | 39.9 | 20.3
| ASW | 31.6 | 47.4 | 21.1
| CHB | 14.6 | 53.3 | 32.1
| CHD | 16.7 | 45.4 | 38.0
| GIH | 6.1 | 37.8 | 56.1
| LWK | 29.6 | 44.4 | 25.9
| MEX | 8.8 | 42.1 | 49.1
| MKK | 20.8 | 46.1 | 33.1
| TSI | 7.1 | 48.5 | 44.4
| HapMapRevision=28
}}[[rs1046089]] is a SNP in the HLA-B associated transcript 2 [[BAT2]] gene.

A study of 2,162 case-controls found an association between [[rs1046089]] and severe [[malaria]].{{PMID|19039607|OA=1
}}

{{PMID Auto GWAS
|PMID=22267201
|Trait=None
|Title=Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.
|RiskAllele=A
|Pval=2E-16
|OR=0.2130
|ORtxt=None
|OA=1
}}

{{PMID Auto
|PMID=18204098
|Title=Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.
}}

{{PMID Auto
|PMID=19143815
|Title=MHC fine mapping of human type 1 diabetes using the T1DGC data.
|OA=1
}}

{{GET Evidence
|gene=PRRC2A
|aa_change=Arg1740His
|aa_change_short=R1740H
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1046089
|n_genomes=33
|n_genomes_annotated=0
|n_haplomes=39
|n_articles=0
|n_articles_annotated=0
|nblosum100=1
|autoscore=1
|webscore=N
}}

{{PMID Auto GWAS
  |PMID=23307926
  |Trait=Menopause (age at onset)
  |Title=A genome-wide association study of early menopause and the combined impact of identified variants.
  |RiskAllele=A
  |Pval=4E-11
  |OR=.19
  |ORtxt=[0.13-0.25] years increase
  |OA=1
}}

{{PMID Auto GWAS
  |PMID=23571483
  |Trait=Schizophrenia
  |Title=A comprehensive family-based replication study of schizophrenia genes.
  |RiskAllele=G
  |Pval=4E-6
  |OR=1.30
  |ORtxt=[NR]
  }}

{{PMID Auto GWAS
  |PMID=23894747
  |Trait=Schizophrenia
  |Title=A comprehensive family-based replication study of schizophrenia genes.
  |RiskAllele=G
  |Pval=4E-6
  |OR=1.30
  |ORtxt=[NR]
  }}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}