{{Rsnum
|rsid=1047840
|Gene=EXO1
|Chromosome=1
|position=241878999
|Orientation=plus
|ReferenceAllele=G
|MissenseAllele=A
|GMAF=0.3609
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=EXO1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 14.2 | 48.7 | 37.2
| HCB | 4.4 | 31.4 | 64.2
| JPT | 7.1 | 33.6 | 59.3
| YRI | 23.8 | 46.3 | 29.9
| ASW | 19.3 | 47.4 | 33.3
| CHB | 4.4 | 31.4 | 64.2
| CHD | 0.9 | 29.4 | 69.7
| GIH | 9.9 | 42.6 | 47.5
| LWK | 42.7 | 40.0 | 17.3
| MEX | 8.6 | 46.6 | 44.8
| MKK | 37.2 | 48.1 | 14.7
| TSI | 10.8 | 41.2 | 48.0
| HapMapRevision=28
}}[[rs1047840]], also known as K589E, is a SNP in the [[EXO1]] gene.

A study of 1,272 [[breast cancer]] Taiwanese patients concluded that the [[rs1047840]](A) allele conferred a significantly (p=0.000025) increased risk of breast cancer.{{PMID|19846925}}

{{PMID Auto
|PMID=19515603
|Title=Interaction of Exo1 genotypes and smoking habit in oral cancer in Taiwan
}}

{{PMID Auto
|PMID=20337148
|Title=Single-nucleotide polymorphism of the Exo1 gene: association with gastric cancer susceptibility and interaction with smoking in Taiwan
}}

{{PMID Auto
|PMID=22146767
|Title=A Single Nucleotide Polymorphism in EXO1 Gene is Associated With Cervical Cancer Susceptibility in Chinese Patients
}}

{{PMID Auto
|PMID=22573488
|Title=EGFR exon 19 in-frame deletion and polymorphisms of DNA repair genes in never-smoking female lung adenocarcinoma patients
}}

{{PMID Auto
|PMID=18079015
|Title=Potentially functional polymorphisms of EXO1 and risk of lung cancer in a Chinese population: A case-control analysis.
}}

{{PMID Auto
|PMID=18191955
|Title=Correlating observed odds ratios from lung cancer case-control studies to SNP functional scores predicted by bioinformatic tools.
|OA=1
}}

{{PMID Auto
|PMID=18559551
|Title=Pathway analysis of single-nucleotide polymorphisms potentially associated with glioblastoma multiforme susceptibility using random forests.
}}

{{PMID Auto
|PMID=19331228
|Title=Lung cancer susceptibility and genetic polymorphisms of Exo1 gene in Taiwan.
}}

{{GET Evidence
|gene=EXO1
|aa_change=Glu589Lys
|aa_change_short=E589K
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1047840
|overall_frequency_n=4402
|overall_frequency_d=10758
|overall_frequency=0.409184
|n_genomes=34
|n_genomes_annotated=0
|n_haplomes=38
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.006
|nblosum100=0
|autoscore=0
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}