{{Rsnum
|rsid=1047972
|Gene=AURKA
|Chromosome=20
|position=56386407
|Orientation=minus
|ReferenceAllele=A
|MissenseAllele=G
|GMAF=0.1561
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=AURKA
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 4.6 | 27.7 | 67.7
| HCB | 0.0 | 0.0 | 0.0
| JPT | 0.0 | 0.0 | 0.0
| YRI | 3.2 | 19.0 | 77.8
| ASW | 0.0 | 0.0 | 0.0
| CHB | 0.0 | 0.0 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}influences mitosis 

associated with [[cancer]]
*{{PMID|16411056}} [[breast cancer]]
*{{PMID|17219423}} [[colorectal cancer]]
*{{PMID|16412566}} [[gastric cancer]]
{{ neighbor
| rsid = 2273535
| distance = 78
}}

{{Venter SNP
|rsid=1047972
|allele=C
|frequency=0.808
|uid=1103643228170
|type=homozygous_SNP
|hugo=AURKA
|ensembl gene=ENSG00000087586
|ensembl transcript=ENST00000347343
|sift=TOLERATED
|disease=Defects in STK6 are responsible for numerical centrosome aberrations including aneuploidy.
}}

{{PMID Auto
|PMID=21050672
|Title=Genetic variants of NPAT-ATM and AURKA are associated with an early adverse reaction in the gastrointestinal tract of patients with cervical cancer treated with pelvic radiation therapy
}}

{{PMID Auto
|PMID=16465622
|Title=Bladder cancer predisposition: a multigenic approach to DNA-repair and cell-cycle-control genes.
|OA=1
}}

{{PMID Auto
|PMID=18854777
|Title=Germline genetic variations in drug action pathways predict clinical outcomes in advanced lung cancer treated with platinum-based chemotherapy.
|OA=1
}}

{{GET Evidence
|gene=AURKA
|aa_change=Ile57Val
|aa_change_short=I57V
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1047972
|overall_frequency_n=8998
|overall_frequency_d=10758
|overall_frequency=0.836401
|n_genomes=53
|n_genomes_annotated=0
|n_haplomes=92
|n_articles=0
|n_articles_annotated=0
|nblosum100=-4
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=25253995
|Title=Association between genetic polymorphisms in AURKA (rs2273535 and rs1047972) and breast cancer risk: a meta-analysis involving 37,221 subjects
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}