{{Rsnum
|rsid=1047978
|Gene=C21orf91
|Chromosome=21
|position=17796838
|Orientation=minus
|GMAF=0.2998
|Gene_s=C21orf91
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 36.9 | 43.1 | 20.0
| HCB | 42.2 | 40.0 | 17.8
| JPT | 38.6 | 50.0 | 11.4
| YRI | 92.1 | 7.9 | 0.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 42.2 | 40.0 | 17.8
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID|22039568|OA=1
}} C21orf91 genotypes correlate with herpes simplex labialis (cold sore) frequency: description of a cold sore susceptibility gene.

{{GET Evidence
|gene=C21ORF91
|aa_change=Asp136Glu
|aa_change_short=D136E
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1047978
|overall_frequency_n=2467
|overall_frequency_d=9536
|overall_frequency=0.258704
|n_genomes=25
|n_genomes_annotated=0
|n_haplomes=33
|n_articles=0
|n_articles_annotated=0
|nblosum100=-2
|autoscore=0
|webscore=N
}}

{{on chip | HumanOmni1Quad}}