{{Rsnum
|rsid=10490162
|Gene=NRXN1
|Chromosome=2
|position=51020519
|Orientation=minus
|GMAF=0.2328
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=NRXN1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 79.6 | 20.4 | 0.0
| HCB | 35.8 | 50.4 | 13.9
| JPT | 28.3 | 49.6 | 22.1
| YRI | 87.1 | 12.9 | 0.0
| ASW | 78.9 | 19.3 | 1.8
| CHB | 35.8 | 50.4 | 13.9
| CHD | 36.7 | 50.5 | 12.8
| GIH | 62.4 | 32.7 | 5.0
| LWK | 77.3 | 22.7 | 0.0
| MEX | 37.9 | 46.6 | 15.5
| MKK | 80.1 | 19.2 | 0.6
| TSI | 82.4 | 17.6 | 0.0
| HapMapRevision=28
}}

rs10490162 increases susceptibility to Substance dependence, Nicotine 1.65 times for carriers of the C allele {{PMID|17158188|OA=1
}}

{{PMID Auto
|PMID=17903299
|Title=A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study.
|OA=1
}}

{{PMID Auto
|PMID=18270208
|Title=Significant association of the neurexin-1 gene (NRXN1) with nicotine dependence in European- and African-American smokers.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}