{{Rsnum
|rsid=1049623
|Gene=DDR1
|Chromosome=6
|position=30897052
|Orientation=minus
|GMAF=0.4927
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=DDR1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 38.9 | 43.4 | 17.7
| HCB | 10.9 | 49.6 | 39.4
| JPT | 15.9 | 46.0 | 38.1
| YRI | 29.3 | 53.1 | 17.7
| ASW | 31.6 | 56.1 | 12.3
| CHB | 10.9 | 49.6 | 39.4
| CHD | 9.2 | 44.0 | 46.8
| GIH | 11.9 | 36.6 | 51.5
| LWK | 21.8 | 46.4 | 31.8
| MEX | 19.0 | 48.3 | 32.8
| MKK | 23.1 | 51.9 | 25.0
| TSI | 33.3 | 51.0 | 15.7
| HapMapRevision=28
}}{{PMID|17440435}} [[schizophrenia]] [[rs1049623]] associated with schizophrenia (odds ratio=1.44, 95% confidence interval: 1.15-1.79, adjusted P=0.0016). 

{{PMID|17440435}} [[schizophrenia]] the SNPs ([[rs1049623]], [[rs2267641]] and [[rs2239518]]) haplotype remaining significant even after adjustment for multiple testing (adjusted P=0.0136).
{{ neighbor
| rsid = 2267641
| distance = 375
}}

{{PharmGKB
|RSID=rs1049623
|Name_s=exon 15 V599V, c.1908T>C, c.1797T>C, mRNA 2130T>C, mRNA 2167T>C, mRNA 1950T>C, p.Val599Val, p.Val636Val
|Gene_s=DDR1
|Feature=
|Evidence=PubMed ID:19837266
|Annotation=Risk or phenotype-associated allele, tested allele: unspecified; minor allele designation varies by ethnicity in dbSNP Phenotype: In 114 cases and 414 controls (n = 528), univariate analysis of disease association showed OR = 0.69 for heterozygote, OR = 1.04 for homozygous, versus homozygous wild type, in ALL, with P(trend) OR = 0.96, p = 0.78 using an additive model. Study size: 528. Study population/ethnicity: Childhood acute lymphoblastic leukemia (<=14 years) and healthy newborn controls (1988 to 1999) from South Wales in the United Kingdom. Significance metric(s): Non-significant finding p = 0.78. Type of association: CO.
|Drugs=
|Drug Classes=
|Diseases=Precursor Cell Lymphoblastic Leukemia-Lymphoma
|Curation Level=Curated
|PharmGKB Accession ID=PA165110231
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1049623
|overall_frequency_n=4353
|overall_frequency_d=10758
|overall_frequency=0.404629
|n_genomes=38
|n_genomes_annotated=0
|n_haplomes=49
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}