{{Rsnum
|rsid=10503669
|Chromosome=8
|position=19990179
|Orientation=plus
|GMAF=0.09275
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 3.5 | 15.9 | 80.5
| HCB | 0.7 | 17.5 | 81.8
| JPT | 0.9 | 17.7 | 81.4
| YRI | 0.0 | 7.5 | 92.5
| ASW | 0.0 | 14.0 | 86.0
| CHB | 0.7 | 17.5 | 81.8
| CHD | 0.9 | 22.0 | 77.1
| GIH | 0.0 | 17.8 | 82.2
| LWK | 0.9 | 4.5 | 94.5
| MEX | 0.0 | 10.3 | 89.7
| MKK | 0.0 | 7.7 | 92.3
| TSI | 2.9 | 18.6 | 78.4
| HapMapRevision=28
}}

Repeatedly associated with elevated lipids according to {{PMID|19161620|OA=1
}}

A allele is associated with 2.09mg/dl increase in [[HDL cholesterol]] (good cholesterol). {{PMID|18193043}}

{{PMID Auto GWAS
|PMID=18193043
|Trait=HDL cholesterol
|Title=Newly identified loci that influence lipid concentrations and risk of coronary artery disease
|RiskAllele=A
|Pval=3.9999999999999999E-19
|OR=2.09
|ORtxt=[NR] mg/dl higher
}}

{{PMID Auto GWAS
|PMID=21909109
|Trait=None
|Title=Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.
|RiskAllele=T
|Pval=7E-39
|OR=0.0857
|ORtxt=[0.073-0.098] mg/dL decrease
}}

{{PMID Auto
|PMID=17903299
|Title=A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study.
|OA=1
}}

{{PMID Auto
|PMID=18852197
|Title=Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.
|OA=1
}}

{{PMID Auto
|PMID=19041386
|Title=Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.
|OA=1
}}

{{PMID Auto
|PMID=19197348
|Title=Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.
|OA=1
}}

{{PMID Auto
|PMID=19474294
|Title=Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.
|OA=1
}}

{{PMID Auto
|PMID=19656773
|Title=A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia.
|OA=1
}}

{{PMID Auto
|PMID=20018038
|Title=Evaluation of genetic risk scores for lipid levels using genome-wide markers in the Framingham Heart Study.
|OA=1
}}

{{PMID Auto
|PMID=20370913
|Title=Genome-wide association analysis of total cholesterol and high-density lipoprotein cholesterol levels using the Framingham heart study data.
|OA=1
}}

{{PMID Auto
|PMID=21347282
|Title=Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs10503669
|overall_frequency_n=8
|overall_frequency_d=128
|overall_frequency=0.0625
|n_genomes=7
|n_genomes_annotated=0
|n_haplomes=8
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23150898
|Title=Evaluation of seven common lipid associated loci in a large Indian sib pair study
|OA=1
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}