{{Rsnum
|rsid=10507391
|Gene=ALOX5AP
|Chromosome=13
|position=30737959
|Orientation=plus
|GMAF=0.489
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;T)
|geno3=(T;T)
|Gene_s=ALOX5AP
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;T)
| geno3=(T;T)
| CEU | 11.5 | 43.4 | 45.1
| HCB | 14.6 | 51.8 | 33.6
| JPT | 10.6 | 38.1 | 51.3
| YRI | 84.4 | 13.6 | 2.0
| ASW | 61.4 | 35.1 | 3.5
| CHB | 14.6 | 51.8 | 33.6
| CHD | 12.8 | 46.8 | 40.4
| GIH | 13.9 | 52.5 | 33.7
| LWK | 80.0 | 19.1 | 0.9
| MEX | 24.1 | 60.3 | 15.5
| MKK | 67.9 | 28.2 | 3.8
| TSI | 13.7 | 55.9 | 30.4
| HapMapRevision=28
}}[[rs10507391]], also known as SG13S114, is an [[ALOX5AP]] gene SNP that has been defined as part of a haplotype potentially associated with risk for [[myocardial infarction]] or ischemic [[stroke]]. Details of this haplotype and several related studies are on the [[ALOX5AP]] page.

One study that specifically found association for [[rs10507391]] involved 639 German ischemic [[stroke]] patients. The association was statistically significant (only) in males, with an odds ratio of 1.24 (CI: 1.04-1.55, p=0.017).{{PMID|15731479}}

{{PMID Auto
|PMID=20067482
|Title=The role of LTA4H and ALOX5AP genes in the risk for asthma in Latinos
|OA=1
}}

{{PMID Auto
|PMID=21153769
|Title=A tagging SNP in ALOX5AP and risk of stroke: a haplotype-based analysis among eastern Chinese Han population
}}

{{PMID Auto
|PMID=22051033
|Title=ALOX5AP genetic variants and risk of atherothrombotic stroke in the Taiwanese population
}}

{{PMID|17903304|OA=1
}} Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes.

{{PMID|19130089|OA=1
}} Genetic effects in the leukotriene biosynthesis pathway and association with atherosclerosis.

{{PMID|19665766|OA=1
}} Genetics and pharmacogenetics of the leukotriene pathway.

{{PMID|20592751|OA=1
}} Human lipoxygenase pathway gene variation and association with markers of subclinical atherosclerosis in the diabetes heart study.

{{PMID|20810156|OA=1
}} ALOX5AP and LTA4H polymorphisms modify augmentation of bronchodilator responsiveness by leukotriene modifiers in Latinos.

{{PMID Auto
|PMID=23765972
|Title=Interaction between ALOX5AP-SG13S114A/T and COX-2-765G/C increases susceptibility to cerebral infarction in a Chinese population
}}

{{PMID Auto
|PMID=24368493
|Title=Interaction between ALOX5AP and CYP3A5 gene variants significantly increases the risk for cerebral infarctions in Chinese
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
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{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
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