{{Rsnum
|rsid=10508503
|Chromosome=10
|position=16299951
|Orientation=plus
|GMAF=0.04132
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}
{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 82.3 | 17.7 | 0.0
| HCB | 100.0 | 0.0 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 100.0 | 0.0 | 0.0
| ASW | 94.7 | 5.3 | 0.0
| CHB | 100.0 | 0.0 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 98.0 | 2.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 91.4 | 8.6 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 82.0 | 18.0 | 0.0
| HapMapRevision=28
}}
{{PMID Auto GWAS
|PMID=19151714
|Trait=Obesity
|Title=Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations
|RiskAllele=C
|Pval=2E-7
|OR=1.56
|ORtxt=[1.10-2.78]
}}

{{omim
|desc=BODY MASS INDEX QUANTITATIVE TRAIT LOCUS 8; BMIQ8
|id=603188
|rsnum=10508503
}}

{{PharmGKB
|RSID=rs10508503
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19174833
|Annotation=The analyses of genome-wide association data from 1,380 Europeans with early-onset and morbid adult obesity and 1,416 age-matched normal-weight controls found an association of this variant (rs10508503) near PTER for risk of pooled childhood and adult severe obesity.
|Drugs=
|Drug Classes=
|Diseases=Obesity
|Curation Level=Curated
|PharmGKB Accession ID=PA162565813
}}

{{PharmGKB
|RSID=rs10508503
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19151714; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations. (Initial Sample Size: 695 obese adults, 685 obese children, 731 lean adults, 685 lean children; Replication Sample Size: 1,171 obese adults, 896 obese children, 1,114 lean adults, 1,297 lean children, 4,417 adults, 5,291 children); (Region: 10p13; Reported Gene(s): PTER; Risk Allele: rs10508503-C); (p-value= 0.0000002).This variant is associated with Obesity.
|Drugs=
|Drug Classes=
|Diseases=Obesity
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740071
}}

{{PMID Auto
|PMID=21912638
|Title=Studies of metabolic phenotypic correlates of 15 obesity associated gene variants
|OA=1
}}

{{PMID Auto
|PMID=19553259
|Title=Common body mass index-associated variants confer risk of extreme obesity.
|OA=1
}}

{{PMID Auto
|PMID=20127379
|Title=From monogenic to polygenic obesity: recent advances.
|OA=1
}}

{{PMID Auto
|PMID=20712903
|Title=Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study.
|OA=1
}}

{{PMID Auto
|PMID=22430306
|Title=Evaluation of common genetic variants identified by GWAS for early onset and morbid obesity in population-based samples.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs10508503
|overall_frequency_n=7
|overall_frequency_d=128
|overall_frequency=0.0546875
|n_genomes=6
|n_genomes_annotated=0
|n_haplomes=7
|n_articles=1
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{PMID Auto
|PMID=23471855
|Title=The genetics of childhood obesity and interaction with dietary macronutrients.
|OA=1
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}