{{Rsnum
|rsid=1051042
|Gene=OAS1
|Chromosome=12
|position=112919432
|Orientation=plus
|GMAF=0.2181
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=OAS1
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 38.5 | 50.8 | 10.8
| HCB | 38.6 | 52.3 | 9.1
| JPT | 63.6 | 36.4 | 0.0
| YRI | 100.0 | 0.0 | 0.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 38.6 | 52.3 | 9.1
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=20079393
|Title=2'-5'-Oligoadenylate synthetase single-nucleotide polymorphisms and haplotypes are associated with variations in immune responses to rubella vaccine
|OA=1
}}

{{PMID|15732009|OA=1
}} Variation in antiviral 2',5'-oligoadenylate synthetase (2'5'AS) enzyme activity is controlled by a single-nucleotide polymorphism at a splice-acceptor site in the OAS1 gene.

{{PMID|19247438|OA=1
}} Genetic variation in OAS1 is a risk factor for initial infection with West Nile virus in man.

{{GET Evidence
|gene=OAS1
|aa_change=Arg361Thr
|aa_change_short=R361T
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1051042
|overall_frequency_n=7944
|overall_frequency_d=10758
|overall_frequency=0.738427
|n_genomes=5
|n_genomes_annotated=0
|n_haplomes=6
|n_articles=0
|n_articles_annotated=0
|nblosum100=3
|autoscore=0
|webscore=N
}}

{{on chip | HumanOmni1Quad}}