{{Rsnum
|rsid=10515807
|Gene=ADRA1B
|Chromosome=5
|position=159937991
|Orientation=minus
|GMAF=0.1933
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=ADRA1B,LOC101927790
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 72.3 | 23.1 | 4.6
| HCB | 50.0 | 36.4 | 13.6
| JPT | 46.5 | 39.5 | 14.0
| YRI | 93.6 | 6.4 | 0.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 50.0 | 36.4 | 13.6
| CHD | 0.0 | 0.0 | 0.0
| GIH | 66.7 | 30.3 | 3.0
| LWK | 91.5 | 7.5 | 0.9
| MEX | 0.0 | 0.0 | 0.0
| MKK | 94.1 | 5.2 | 0.7
| TSI | 62.9 | 34.0 | 3.1
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs10515807
|Name_s=
|Gene_s=ADRA1B
|Feature=
|Evidence=PubMed ID:19910028
|Annotation=in a GWAS of subjects of African ancestry(African American plus African Caribbean), this SNP was found to be significantly associated with Asthma . This finding was not significantly replicated in 4 additional case-control studies of African Americans nor in tested family and case-control panels of UK and German subjects. Risk or phenotype-associated allele: T. Phenotype: increased risk for asthma. Study size/population/ethnicity: 1) 935 African American asthmatic cases and control subjects from the Baltimore-Washington area (2) 929 African Caribbean asthmatic subjects and their family members from Barbados . Significance metric(s): combined p = 3.57 x 10(-6); OR = 1.40(95% CI= 1.18-1.66). Type of association: CO; GN.
|Drugs=
|Drug Classes=
|Diseases=Asthma
|Curation Level=Curated
|PharmGKB Accession ID=PA165111740
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs10515807
|overall_frequency_n=15
|overall_frequency_d=128
|overall_frequency=0.117188
|n_genomes=12
|n_genomes_annotated=0
|n_haplomes=12
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}