{{Rsnum
|rsid=10515860
|Gene=HMMR
|Chromosome=5
|position=163490702
|Orientation=plus
|GMAF=0.07071
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=HMMR,HMMR-AS1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 1.8 | 25.0 | 73.2
| HCB | 0.0 | 6.6 | 93.4
| JPT | 0.0 | 6.2 | 93.8
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 8.8 | 91.2
| CHB | 0.0 | 6.6 | 93.4
| CHD | 0.9 | 11.9 | 87.2
| GIH | 1.0 | 24.8 | 74.3
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 20.7 | 79.3
| MKK | 0.0 | 1.9 | 98.1
| TSI | 1.0 | 13.7 | 85.3
| HapMapRevision=28
}}
[http://cancergenetics.wordpress.com/2007/10/13/exciting-discoveries-of-2007-breast-cancer/ cancergenetics] The risk of [[breast cancer]] was 23% higher in women who had one copy of genetic variant (the A-C-A haplotype: [[rs7712023]]-[[rs299290]]-[[rs10515860]]), and 46% higher in women with two copies. In addition, those women were diagnosed an average of 12 months younger than women from the control group, suggesting that [[HMMR]] is linked to early-onset breast cancer.

However, a more recent, larger European case-control study found no association between [[rs10515860]] and risk of breast cancer.{{PMID|19065580}}

{{PMID|19064580}} [[breast cancer]]
*[[rs10515860]] [odds ratio (OR; AA/GG), 0.85; 95% confidence interval (CI), 0.65-1.12; P(trend) = 0.9], 
*[[rs299290]] [OR (CC/TT), 1.00; 95% CI, 0.87-1.15; P(trend) = 0.7], 
*[[rs3756648]] ([[rs7712023]]) [OR (TT/CC), 0.93; 95% CI, 0.84-1.02; P(trend) = 0.1], 
*[[rs299284]] [OR (TT/CC), 1.01; 95% CI, 0.76-1.35; P(trend) = 0.5], and *[[rs13183712]] [OR (TT/GG), 1.04; 95% CI, 0.88-1.23; P(trend) = 0.6].

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}