{{Rsnum
|rsid=1053874
|Gene=DNASE1
|Chromosome=16
|position=3657746
|Orientation=plus
|GMAF=0.4862
|Gene_s=DNASE1,TRAP1
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 8.8 | 45.1 | 46.0
| HCB | 18.7 | 54.5 | 26.9
| JPT | 26.8 | 57.1 | 16.1
| YRI | 76.7 | 21.2 | 2.1
| ASW | 68.4 | 28.1 | 3.5
| CHB | 18.7 | 54.5 | 26.9
| CHD | 19.4 | 46.3 | 34.3
| GIH | 19.8 | 55.4 | 24.8
| LWK | 71.6 | 24.8 | 3.7
| MEX | 19.0 | 44.8 | 36.2
| MKK | 40.4 | 50.6 | 9.0
| TSI | 8.9 | 35.6 | 55.4
| HapMapRevision=28
}}{{omim
|id=125505
|rsnum=1053874
|variant=0002
}}

{{ClinVar
|rsid=1053874
|Reversed=0
|FwdREF=G
|FwdALT=A
|REF=G
|ALT=A
|RSPOS=3707747
|CHROM=16
|GMAF=0.4863
|dbSNPBuildID=86
|SSR=0
|SAO=1
|VP=0x05036800000017051f110100
|GENEINFO=TRAP1:10131; DNASE1:1773
|GENE_NAME=TRAP1; DNASE1
|GENE_ID=10131; 1773
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000016.9:g.3707747G>A
|CLNORIGIN=1
|CLNSIG=255
|Tags=PM;PMC;S3D;SLO;VLD;G5A;G5;HD;GNO;KGPhase1;KGPilot123;KGPROD;OTHERKG;PH3;LSD;OM
|CAF=0.5138; 0.4862
|CLNACC=RCV000018346.1
|CLNDBN=Systemic lupus erythematosus, susceptibility to
|CLNSRC=OMIM Allelic Variant
|CLNSRCID=125505.0002
|COMMON=1
|Disease=Systemic lupus erythematosus
}}

{{PMID Auto
|PMID=15569484
|Title=Single nucleotide polymorphisms of deoxyribonuclease I and their expression in Chinese systemic lupus erythematosus patients.
}}

{{PMID Auto
|PMID=16449364
|Title=Association of a non-synonymous single-nucleotide polymorphism of DNASEI with SLE susceptibility.
}}

{{GET Evidence
|gene=DNASE1
|aa_change=Arg244Gln
|aa_change_short=R244Q
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1053874
|overall_frequency_n=4877
|overall_frequency_d=10758
|overall_frequency=0.453337
|n_genomes=45
|n_genomes_annotated=0
|n_haplomes=66
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.145
|nblosum100=0
|autoscore=0
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}