{{Rsnum
|rsid=1061646
|Gene=FANCA
|Chromosome=16
|position=89739569
|Orientation=minus
|GMAF=0.4775
|Gene_s=FANCA,ZNF276
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 40.7 | 44.2 | 15.0
| HCB | 2.2 | 41.6 | 56.2
| JPT | 0.9 | 29.2 | 69.9
| YRI | 14.0 | 45.5 | 40.6
| ASW | 33.3 | 35.1 | 31.6
| CHB | 2.2 | 41.6 | 56.2
| CHD | 6.4 | 42.2 | 51.4
| GIH | 17.8 | 52.5 | 29.7
| LWK | 15.7 | 48.1 | 36.1
| MEX | 24.1 | 44.8 | 31.0
| MKK | 21.8 | 53.2 | 25.0
| TSI | 63.7 | 32.4 | 3.9
| HapMapRevision=28
}}{{PMID|18056155}} [[breast cancer]] [[rs1061646]] was associated with risk in the initial study (p=0.0052), and in the replication studies (p=0.032). In a combined analysis, (8,556 cases, 9,605 controls) this SNP yielded an 8% increase in risk per allele. Note that this analysis was carried out in a multi-ethnic study, and [[rs1061646]] showed more consistent association with risk in non-Caucasian populations.

{{PMID Auto
|PMID=18701435
|Title=Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}