{{Rsnum
|rsid=1062202
|Gene=C21orf91
|Chromosome=21
|position=17792325
|Orientation=minus
|GMAF=0.3733
|Gene_s=C21orf91
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 4.5 | 45.5 | 50.0
| HCB | 0.0 | 0.0 | 0.0
| JPT | 0.0 | 0.0 | 0.0
| YRI | 31.2 | 49.3 | 19.4
| ASW | 17.9 | 64.3 | 17.9
| CHB | 0.0 | 0.0 | 0.0
| CHD | 20.4 | 46.3 | 33.3
| GIH | 6.0 | 37.0 | 57.0
| LWK | 21.8 | 51.8 | 26.4
| MEX | 22.4 | 41.4 | 36.2
| MKK | 12.9 | 37.4 | 49.7
| TSI | 4.0 | 41.6 | 54.5
| HapMapRevision=28
}}{{PMID|22039568|OA=1
}} http://jid.oxfordjournals.org/content/204/11/1654.long 
This analysis revealed a strong association between the frequently affected phenotype and the C allele of SNP [[rs1062202]] (?2 = 8.0, P = .0047), predicted to lie in the 3? UTR of C21orf91 (Figure 2, Table 1). Another SNP, [[rs10446073]], which was approximately 1 kb upstream of the start site of transcription of C21orf91, also showed a moderate association (?2 = 3.57, P = .06) with the cold-sore phenotype.

{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}