{{Rsnum
|rsid=1064039
|Gene=CST3
|Chromosome=20
|position=23637790
|Orientation=minus
|GMAF=0.1892
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=CST3
}}{{omim
|id=604312
|rsnum=1064039
|variant=0002
}}

{{ClinVar
|rsid=1064039
|Reversed=1
|FwdREF=G
|FwdALT=A
|REF=C
|ALT=T
|RSPOS=23618427
|CHROM=20
|GMAF=0.1896
|dbSNPBuildID=86
|SSR=0
|SAO=1
|VP=0x050168000000110116110100
|GENEINFO=CST3:1471
|GENE_NAME=CST3
|GENE_ID=1471
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000020.10:g.23618427C>T
|CLNSRC=OMIM Allelic Variant
|CLNORIGIN=1
|CLNSRCID=604312.0002
|CLNSIG=5
|CLNCUI=C2677774
|CLNDBN=Age-related macular degeneration 11
|Disease=Age-related macular degeneration 11
|CLNACC=RCV000005989.1
|Tags=RV;PM;PMC;SLO;G5;GNO;KGPhase1;KGPROD;OTHERKG;LSD;OM
|CAF=0.8108; 0.1892
|CLNDSDB=MedGen:OMIM
|CLNDSDBID=C2677774:611953
|COMMON=1
}}

{{PMID Auto
|PMID=18830724
|Title=Assessment of Alzheimer's disease case-control associations using family-based methods.
|OA=1
}}

{{PMID Auto
|PMID=22435454
|Title=Meta-Analysis of the Cystatin C(CST3) Gene G73A Polymorphism and Susceptibility to Alzheimer's Disease.
}}

{{GET Evidence
|gene=CST3
|aa_change=Ala25Thr
|aa_change_short=A25T
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1064039
|overall_frequency_n=1579
|overall_frequency_d=9258
|overall_frequency=0.170555
|n_genomes=2
|n_genomes_annotated=0
|n_haplomes=1
|n_articles=0
|n_articles_annotated=0
|in_omim=Y
|nblosum100=1
|autoscore=2
|webscore=N
|summary_short=Associated with age-related macular degeneration and alzheimer's disease.
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}