{{Rsnum
|rsid=10755578
|Gene=LPA
|Chromosome=6
|position=160548706
|Orientation=plus
|GMAF=0.4118
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=LPA
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 25.7 | 47.8 | 26.5
| HCB | 27.7 | 52.6 | 19.7
| JPT | 27.7 | 53.6 | 18.8
| YRI | 43.5 | 49.7 | 6.8
| ASW | 40.4 | 47.4 | 12.3
| CHB | 27.7 | 52.6 | 19.7
| CHD | 34.9 | 39.4 | 25.7
| GIH | 29.7 | 52.5 | 17.8
| LWK | 41.8 | 50.0 | 8.2
| MEX | 46.6 | 44.8 | 8.6
| MKK | 28.2 | 59.6 | 12.2
| TSI | 30.4 | 48.0 | 21.6
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs10755578
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19198611; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. (Initial Sample Size: 1,926 cases, 2,938 controls; Replication Sample Size: 7,073 cases, 7,325 controls); (Region: 6q25.3; Reported Gene(s): SLC22A3,LPAL2,LPA; Risk Allele: 4-SNP haplotype-1); (p-value= 0.000000001).This variant is associated with Coronary artery disease.
|Drugs=
|Drug Classes=
|Diseases=Cardiovascular Diseases
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164739975
}}

{{PharmGKB
|RSID=rs10755578
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19198611; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. (Initial Sample Size: 1,926 cases, 2,938 controls; Replication Sample Size: 7,073 cases, 7,325 controls); (Region: 6q25.3; Reported Gene(s): SLC22A3,LPAL2,LPA; Risk Allele: 4-SNP haplotype-2); (p-value= 0.000000000000004).This variant is associated with Coronary artery disease.
|Drugs=
|Drug Classes=
|Diseases=Cardiovascular Diseases
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164739981
}}

{{PMID Auto
|PMID=19956433
|Title=Genetics of coronary artery disease: focus on genome-wide association studies.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs10755578
|overall_frequency_n=4538
|overall_frequency_d=10754
|overall_frequency=0.421983
|n_genomes=31
|n_genomes_annotated=0
|n_haplomes=40
|n_articles=0
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}