{{Rsnum
|rsid=10758593
|Gene=GLIS3
|Chromosome=9
|position=4292083
|Orientation=plus
|GMAF=0.4564
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}
{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 21.6 | 49.5 | 28.8
| HCB | 20.7 | 40.0 | 39.3
| JPT | 19.5 | 51.3 | 29.2
| YRI | 19.9 | 52.1 | 28.1
| ASW | 26.3 | 42.1 | 31.6
| CHB | 20.7 | 40.0 | 39.3
| CHD | 21.1 | 50.5 | 28.4
| GIH | 30.7 | 47.5 | 21.8
| LWK | 31.8 | 45.5 | 22.7
| MEX | 25.9 | 58.6 | 15.5
| MKK | 41.3 | 43.2 | 15.5
| TSI | 28.7 | 43.6 | 27.7
| HapMapRevision=28
}}
{{PMID Auto GWAS
|PMID=18840781
|Trait=Type 1 diabetes
|Title=Follow up analysis of genome-wide association data identifies novel loci for type 1 diabetes
|RiskAllele=A
|Pval=0.0000030000000000000001
|OR=1.13
|ORtxt=[1.07-1.19]
|OA=1
}}

{{PharmGKB
|RSID=rs10758593
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:18840781; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=Follow up analysis of genome-wide association data identifies novel loci for type 1 diabetes. (Initial Sample Size: 563 cases, 1,146 controls, 483 case-parents trios; Replication Sample Size: 636 families, 3,303 cases, 4,673 controls); (Region: 9p24.2; Reported Gene: GLIS3; Risk Allele: rs10758593-A) This variant is associated with Type 1 diabetes.
|Drugs=
|Drug Classes=
|Diseases=Diabetes Mellitus, Type 1
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740882
}}

{{PharmGKB
|RSID=rs10758593
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:18840781; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Follow up analysis of genome-wide association data identifies novel loci for type 1 diabetes. (Initial Sample Size: 563 cases, 1,146 controls, 483 case-parents trios; Replication Sample Size: 636 families, 3,303 cases, 4,673 controls); (Region: 9p24.2; Reported Gene(s): GLIS3; Risk Allele: rs10758593-A); (p-value= 0.000003).This variant is associated with Type 1 diabetes.
|Drugs=
|Drug Classes=
|Diseases=Diabetes Mellitus; Diabetes Mellitus, Type 1
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740816
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs10758593
|overall_frequency_n=65
|overall_frequency_d=128
|overall_frequency=0.507812
|n_genomes=43
|n_genomes_annotated=0
|n_haplomes=53
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}