{{Rsnum
|rsid=10759932
|Gene=TLR4
|Chromosome=9
|position=117702866
|Orientation=plus
|GMAF=0.2034
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=TLR4
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 1.6 | 23.8 | 74.6
| HCB | 4.5 | 43.2 | 52.3
| JPT | 9.1 | 31.8 | 59.1
| YRI | 4.8 | 41.9 | 53.2
| ASW | 0.0 | 0.0 | 0.0
| CHB | 4.5 | 43.2 | 52.3
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}
[[rs10759932]] is a SNP in the toll-like receptor 4 [[TLR4]] gene.

A study of 109 pregnant women focusing on [[TLR4]] SNPs associated with [[chorionic plate inflammation]] concluded that [[rs10759932]] was associated with increased risk when present in the mother's genome. The risk allele's increased odds ratio for clinically significant inflammation was 5.2 (CI: 3.2-6.4, p = .006) {{PMID|18928988}}

{{PMID Auto
|PMID=19741468
|Title=Impact of Polymorphisms of TLR4/CD14 and TLR3 on Acute Rejection in Kidney Transplantation
}}

{{PMID Auto
|PMID=20109750
|Title=Host-microbial interactions in childhood atopy: Toll-like receptor 4 (TLR4), CD14, and fecal Escherichia coli
}}

{{PMID Auto
|PMID=20685742
|Title=Toll-like receptor 2 and 4 genes influence susceptibility to adverse effects of traffic-related air pollution on childhood asthma
}}

{{PMID Auto
|PMID=21081146
|Title=Impact of Toll-like receptor 4 polymorphisms on risk of cancer
}}

{{PMID Auto
|PMID=17301271
|Title=Toll-like receptor 4 genetic variation and advanced prostate cancer risk.
}}

{{PMID Auto
|PMID=17699831
|Title=Toll-like receptor 4 polymorphism associated with the response to whole-cell pertussis vaccination in children from the KOALA study.
|OA=1
}}

{{PMID Auto
|PMID=18396467
|Title=Genetic variation and haplotype structures of innate immunity genes in eastern India.
|OA=1
}}

{{PMID Auto
|PMID=19505919
|Title=Toll-like receptor signaling pathway variants and prostate cancer mortality.
|OA=1
}}

{{PMID Auto
|PMID=20200442
|Title=Sequence variants in the TLR4 and TLR6-1-10 genes and prostate cancer risk. Results based on pooled analysis from three independent studies.
|OA=1
}}

{{PMID Auto
|PMID=24108365
|Title=Polymorphism -2604G&gt;A variants in TLR4 promoter are associated with different gene expression level in peripheral blood of atherosclerotic patients
}}

{{PMID Auto
|PMID=23161283
|Title=SNPs in toll-like receptor (TLR) genes as new genetic alterations associated with congenital toxoplasmosis?
|OA=1
}}

{{PMID Auto
|PMID=24929142
|Title=Genetic polymorphisms in the Toll-like receptor signalling pathway in Helicobacter pylori infection and related gastric cancer
}}

{{PMID Auto
|PMID=24269697
|Title=TLR4 polymorphisms associated with developing gastric pre-cancer lesions in a Chinese Han population
}}

{{PMID Auto
|PMID=25217737
|Title=Toll-Like Receptor 4 Polymorphisms in Gram-Negative Bacterial Infections of Han Chinese Neonates
}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}