{{Rsnum
|rsid=1076160
|Gene=TSC1
|Chromosome=9
|position=132900647
|Orientation=minus
|GMAF=0.4146
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=TSC1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 27.4 | 45.1 | 27.4
| HCB | 30.7 | 48.9 | 20.4
| JPT | 24.8 | 53.1 | 22.1
| YRI | 0.0 | 6.8 | 93.2
| ASW | 0.0 | 29.8 | 70.2
| CHB | 30.7 | 48.9 | 20.4
| CHD | 22.0 | 58.7 | 19.3
| GIH | 28.7 | 55.4 | 15.8
| LWK | 0.0 | 5.5 | 94.5
| MEX | 12.3 | 54.4 | 33.3
| MKK | 3.9 | 31.0 | 65.2
| TSI | 22.5 | 47.1 | 30.4
| HapMapRevision=28
}}
{{PMID Auto GWAS
|PMID=19169254
|Trait=Psoriasis
|Title=Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways
|RiskAllele=T
|Pval=0.000006
|OR=1.09
|ORtxt=None
|OA=1
}}

{{PharmGKB
|RSID=rs1076160
|Name_s=
|Gene_s=TSC1
|Feature=
|Evidence=PubMed ID:19169254; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. (Initial Sample Size: 1,359 cases, 1,400 controls; Replication Sample Size: 5,048 cases, 5,041 controls); (Region: 9q34.13; Reported Gene(s): TSC1; Risk Allele: rs1076160-T); (p-value= 0.000006).This variant is associated with Psoriasis.
|Drugs=
|Drug Classes=
|Diseases=Psoriasis
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740041
}}

{{PMID Auto
|PMID=21623003
|Title=Confirmation of TNIP1 and IL23A as susceptibility loci for psoriatic arthritis
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1076160
|overall_frequency_n=49
|overall_frequency_d=128
|overall_frequency=0.382812
|n_genomes=29
|n_genomes_annotated=0
|n_haplomes=38
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | Illumina Human 1M}}