{{Rsnum
|rsid=10761779
|Chromosome=10
|position=65274927
|Orientation=plus
|GMAF=0.3857
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}
{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 33.6 | 41.6 | 24.8
| HCB | 35.0 | 53.3 | 11.7
| JPT | 30.6 | 45.0 | 24.3
| YRI | 58.2 | 31.5 | 10.3
| ASW | 40.4 | 49.1 | 10.5
| CHB | 35.0 | 53.3 | 11.7
| CHD | 38.9 | 50.9 | 10.2
| GIH | 23.7 | 49.5 | 26.8
| LWK | 60.9 | 33.6 | 5.5
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=18940312
|Trait=Plasma levels of liver enzymes
|Title=Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes
|RiskAllele=G
|Pval=7E-10
|OR=0.03
|ORtxt=[0.017-0.033] U/L increase
|OA=1
}}

{{omim
|desc=ALKALINE PHOSPHATASE, PLASMA LEVEL OF, QUANTITATIVE TRAIT LOCUS 4
|id=612369
|rsnum=10761779
}}

{{PharmGKB
|RSID=rs10761779
|Name_s=
|Gene_s=REEP3
|Feature=
|Evidence=PubMed ID:18940312; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. (Initial Sample Size: 7,751 European white individuals; Replication Sample Size: 4,704 European white and Indian Asian individua); (Region: 10q21.2; Reported Gene(s): REEP3; Risk Allele: rs10761779-G); (p-value= 0.0000000007).This variant is associated with Plasma levels of liver enzymes.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740805
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs10761779
|overall_frequency_n=48
|overall_frequency_d=128
|overall_frequency=0.375
|n_genomes=29
|n_genomes_annotated=0
|n_haplomes=39
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}