{{Rsnum
|rsid=10798269
|Gene=LOC100506023
|Chromosome=1
|position=173340574
|Orientation=plus
|GMAF=0.3678
|Gene_s=IGHVII-15-1
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 15.9 | 49.6 | 34.5
| HCB | 10.2 | 49.6 | 40.1
| JPT | 8.8 | 43.4 | 47.8
| YRI | 22.4 | 54.4 | 23.1
| ASW | 17.5 | 56.1 | 26.3
| CHB | 10.2 | 49.6 | 40.1
| CHD | 11.9 | 56.9 | 31.2
| GIH | 11.9 | 44.6 | 43.6
| LWK | 24.5 | 53.6 | 21.8
| MEX | 10.3 | 50.0 | 39.7
| MKK | 21.2 | 51.9 | 26.9
| TSI | 12.9 | 41.6 | 45.5
| HapMapRevision=28
}}One of several SNPs found in a study of ~2,5720 female patients of European ancestry to be associated with systemic [[lupus]] erythematosus.{{PMID|18204446|OA=1
}}

{{GWAS Summary
|SNP=rs10798269
|PubMedID=18204446
|Condition=Systemic lupus erythematosus in women
|Gene=Intergenic
|Risk Allele=
|pValue=1.00E-007
|OR=1.22
|95CI=1.14-1.32
|OA=1
}}

{{PMID Auto
|PMID=19714582
|Title=Rheumatoid arthritis does not share most of the newly identified systemic lupus erythematosus genetic factors
}}

{{PharmGKB
|RSID=rs10798269
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:18204446; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci (Initial Sample Size: 720 cases, 2,337 controls; Replication Sample Size: 1,846 cases, 1,825 controls). This variant is associated with Systemic lupus erythematosus in women.
|Drugs=
|Drug Classes=
|Diseases=Lupus erythematosus; Lupus Erythematosus, Systemic
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA162356484
}}

{{PMID Auto
|PMID=19341491
|Title=Genome-based prediction of common diseases: methodological considerations for future research.
|OA=1
}}

{{PMID Auto
|PMID=19442287
|Title=Replication of recently identified systemic lupus erythematosus genetic associations: a case-control study.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs10798269
|overall_frequency_n=88
|overall_frequency_d=128
|overall_frequency=0.6875
|n_genomes=46
|n_genomes_annotated=0
|n_haplomes=72
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}