{{Rsnum
|rsid=10801047
|Chromosome=1
|position=191590226
|Orientation=plus
|GMAF=0.1878
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;T)
| geno3=(T;T)
| CEU | 0.0 | 19.5 | 80.5
| HCB | 0.7 | 17.5 | 81.8
| JPT | 3.5 | 23.0 | 73.5
| YRI | 22.6 | 45.2 | 32.2
| ASW | 22.8 | 52.6 | 24.6
| CHB | 0.7 | 17.5 | 81.8
| CHD | 0.0 | 18.3 | 81.7
| GIH | 1.0 | 36.6 | 62.4
| LWK | 15.5 | 44.5 | 40.0
| MEX | 3.4 | 34.5 | 62.1
| MKK | 7.1 | 38.1 | 54.8
| TSI | 0.0 | 13.7 | 86.3
| HapMapRevision=28
}}{{GWAS Summary
|SNP=rs10801047
|PubMedID=17554261
|Condition=Crohn's disease
|Gene=Intergenic
|Risk Allele=
|pValue=3.00E-008
|OR=1.47
|95CI=1.22-1.76
|OA=1
}}

{{PharmGKB
|RSID=rs10801047
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:17554261; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility (Initial Sample Size: 1,748 cases, 2,938 controls; Replication Sample Size: 1,182 cases, 2,024 controls). This variant is associated with Crohn's disease.
|Drugs=
|Drug Classes=
|Diseases=Crohn Disease
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA162356576
}}

{{PMID|18853133|OA=1
}} Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.

{{PMID|19140132|OA=1
}} Unbiased estimation of odds ratios: combining genomewide association scans with replication studies.

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs10801047
|overall_frequency_n=88
|overall_frequency_d=120
|overall_frequency=0.733333
|n_genomes=43
|n_genomes_annotated=0
|n_haplomes=70
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}