{{Rsnum
|rsid=10801575
|Gene=LOC100289145
|Chromosome=1
|position=196883651
|Orientation=plus
|GMAF=0.376
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 46.0 | 38.9 | 15.0
| HCB | 63.6 | 28.0 | 8.3
| JPT | 64.6 | 31.9 | 3.5
| YRI | 3.2 | 28.6 | 68.3
| ASW | 15.8 | 33.3 | 50.9
| CHB | 63.6 | 28.0 | 8.3
| CHD | 65.7 | 28.6 | 5.7
| GIH | 37.6 | 44.6 | 17.8
| LWK | 4.7 | 30.8 | 64.5
| MEX | 62.1 | 36.2 | 1.7
| MKK | 7.2 | 41.4 | 51.3
| TSI | 41.2 | 47.1 | 11.8
| HapMapRevision=28
}}

[http://7thspace.com/headlines/283954/the_neincbi_dbgap_database_genotypes_and_haplotypes_that_may_predispose_to_risk_of_neovascular_age_related_macular_degeneration.html news] 

[[rs572515]] was the most significantly associated with AMD risk (P <10-6).

[[rs9288410]] and [[rs2014307]] (PLEKHA1/HTRA1) on 10q26 were significantly associated with AMD status (P= .03 and P <10-6 respectively). After controlling for smoking history, gender and age, the most significant gene-gene interaction appears to be between [[rs10801575]] (CFH) and [[rs2014307]] (PLEKHA1/HTRA1) (P <10-11).

{{PMID Auto
|PMID=18541031
|Title=The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}