{{Rsnum
|rsid=10836235
|Gene=CAT
|Chromosome=11
|position=34439157
|Orientation=plus
|GMAF=0.1534
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=CAT
}}{{PMID Auto
|PMID=19863340
|Title=Influence of the polymorphism in candidate genes on late cardiac damage in patients treated due to acute leukemia in childhood
}}

{{PharmGKB
|RSID=rs10836235
|Name_s=CAT c.66 + 78C > T
|Gene_s=CAT
|Feature=
|Evidence=PubMed ID:19863340
|Annotation=Risk or phenotype-associated allele: C Phenotype: Individuals that were CC homozygotes for CAT c.66 + 78C>T had increased risk of cardiac damage after anthracyline exposure. Study size: 76 Study population/ethnicity: Survivors of childhood leukemia (Precursor Cell Lymphoblastic Leukemia-Lymphoma), Slovenia Significance metric(s): p = 0.02 Type of association: CO; TOX; ADR
|Drugs=
|Drug Classes=ANTHRACYCLINES AND RELATED SUBSTANCES
|Diseases=Cardiomyopathies; Drug Toxicity; Precursor Cell Lymphoblastic Leukemia-Lymphoma
|Curation Level=Curated
|PharmGKB Accession ID=PA165291527
}}

{{PMID Auto
|PMID=20416077
|Title=Identification of type 2 diabetes-associated combination of SNPs using support vector machine.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs10836235
|overall_frequency_n=13
|overall_frequency_d=124
|overall_frequency=0.104839
|n_genomes=9
|n_genomes_annotated=0
|n_haplomes=12
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}