{{Rsnum
|rsid=10975200
|Gene=KANK1
|Chromosome=9
|position=571085
|Orientation=plus
|GMAF=0.3191
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}
{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 69.0 | 29.2 | 1.8
| HCB | 18.2 | 50.4 | 31.4
| JPT | 37.2 | 51.3 | 11.5
| YRI | 47.6 | 42.2 | 10.2
| ASW | 50.9 | 40.4 | 8.8
| CHB | 18.2 | 50.4 | 31.4
| CHD | 12.8 | 47.7 | 39.4
| GIH | 76.8 | 20.2 | 3.0
| LWK | 50.9 | 36.4 | 12.7
| MEX | 53.4 | 37.9 | 8.6
| MKK | 52.3 | 37.4 | 10.3
| TSI | 69.6 | 26.5 | 3.9
| HapMapRevision=28
}}

{{PharmGKB
|RSID=rs10975200
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:17660530
|Annotation=In a replicated GWAS of U.K. and U.S. case/parent trios, this variant was shown to be associated with multiple sclerosis risk.
|Drugs=
|Drug Classes=
|Diseases=Multiple Sclerosis
|Curation Level=Curated
|PharmGKB Accession ID=PA162356168
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs10975200
|overall_frequency_n=34
|overall_frequency_d=126
|overall_frequency=0.269841
|n_genomes=28
|n_genomes_annotated=0
|n_haplomes=35
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | Affy500k}}

This SNP is located in the gene [[KANK1]]. This variant has been associated with risk of [[Multiple Sclerosis]] {{PMID|17660530}}. The study analyzed 931 family trios and several different control sets. The p-value for the association was 9.945e-06 [[http://www.gwascentral.org/marker/HGVM3682090/results]].