{{Rsnum
|rsid=10989591
|Gene=GRIN3A
|Chromosome=9
|position=101686816
|Orientation=plus
|GMAF=0.2998
|Gene_s=GRIN3A
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 49.6 | 41.6 | 8.8
| HCB | 89.1 | 10.2 | 0.7
| JPT | 58.4 | 38.1 | 3.5
| YRI | 24.7 | 57.5 | 17.8
| ASW | 29.8 | 52.6 | 17.5
| CHB | 89.1 | 10.2 | 0.7
| CHD | 88.1 | 11.9 | 0.0
| GIH | 38.6 | 55.4 | 5.9
| LWK | 14.5 | 59.1 | 26.4
| MEX | 60.3 | 32.8 | 6.9
| MKK | 26.3 | 55.8 | 17.9
| TSI | 35.3 | 51.0 | 13.7
| HapMapRevision=28
}}[[rs10989591]], aka Val362Met or V362M, is a SNP in the N-methyl-D-aspartate 3A [[GRIN3A]] gene, which codes for the N-methyl-D-aspartate 3A subunit of the glutamate N-methyl-D-aspartate receptor. The (C) allele encodes the Val and the (T) allele encodes the Met.

[[gs278]] reflects a gene-gene interaction between this SNP and a DRD2 SNP, [[rs6277]], in which older adults with a particular combination of genotypes at these two (independent) loci are reported to exhibit better episodic memory.

{{PMID|17214563}} Based on electromagnetic activity during selective attention (auditory oddball task with target processing) measured in 281 healthy subjects, [[rs10989591]](T;T) individuals appeared to show better prefrontal information processing (based on higher frontal P300 amplitudes), presumably reflecting higher NMDA receptor efficacy.

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}