{{Rsnum
|rsid=10995190
|Gene=ZNF365
|Chromosome=10
|position=64278682
|Orientation=plus
|GMAF=0.1171
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}
{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 1.8 | 22.1 | 76.1
| HCB | 0.0 | 3.6 | 96.4
| JPT | 0.0 | 9.7 | 90.3
| YRI | 1.4 | 32.7 | 66.0
| ASW | 7.0 | 26.3 | 66.7
| CHB | 0.0 | 3.6 | 96.4
| CHD | 0.0 | 1.9 | 98.1
| GIH | 0.0 | 22.8 | 77.2
| LWK | 3.6 | 31.8 | 64.5
| MEX | 0.0 | 12.1 | 87.9
| MKK | 3.2 | 29.7 | 67.1
| TSI | 0.0 | 29.4 | 70.6
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=20453838
|Trait=Breast cancer
|Title=Genome-wide association study identifies five new breast cancer susceptibility loci
|RiskAllele=G
|Pval=5E-15
|OR=1.16
|ORtxt=[1.10-1.22]
|OA=1
}}
[http://blog.23andme.com/2011/02/16/snpwatch-researchers-identify-variant-associated-with-breast-density/ 23andMe blog] each copy of an A at rs10995190 was associated with a 2% decrease in mammographic density. The researchers also found that each copy of an A at rs10995190 is also associated with slightly lower odds of developing [[breast cancer]]

{{PMID Auto
|PMID=21445572
|Title=Genetic polymorphisms and breast cancer risk: evidence from meta-analyses, pooled analyses, and genome-wide association studies
}}

{{PMID Auto GWAS
|PMID=21278746
|Trait=None
|Title=Common variants in ZNF365 are associated with both mammographic density and breast cancer risk
|RiskAllele=A
|Pval=1E-9
|OR=0.1800
|ORtxt=[0.12-0.25] % decrease
|OA=1
}}

{{PMID Auto
|PMID=22348646
|Title=Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers
|OA=1
}}

{{PMID Auto
|PMID=22461340
|Title=11q13 is a susceptibility locus for hormone receptor positive breast cancer
|OA=1
}}

[[Breast Cancer Risk Modifiers]]

{{PMID Auto GWAS
  |PMID=23535733
  |Trait=Breast cancer
  |Title=Genome-wide association studies identify four ER negative-specific breast cancer risk loci.
  |RiskAllele=G
  |Pval=1E-7
  |OR=1.12
  |ORtxt=[1.08-1.18]
  |OA=1
}}

{{PMID Auto GWAS
  |PMID=23535729
  |Trait=Breast cancer
  |Title=Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
  |RiskAllele=G
  |Pval=1E-36
  |OR=1.16
  |ORtxt=[1.14-1.19]
  |OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}